{"title":"Synergistic Research Kits","description":"","products":[{"product_id":"bpc-157-tb500-bacteriostatic-water-research-kit","title":"BPC-157 + TB500 + Bacteriostatic Water Research Kit","description":"\u003cp\u003e\u003cstrong\u003eCertificate of Analysis (COA): See Images \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe Complete Research Protocol: BPC-157, TB-500 \u0026amp; Solvent.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis research bundle provides the three essential components required for high-level regenerative study: 5mg of BPC-157, 5mg of TB-500, and 10ml of Bacteriostatic Water. By supplying these compounds in their pure, lyophilized states alongside the necessary solvent, researchers can ensure maximum stability and precise concentration control at the time of reconstitution.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMPORTANT: Why We Do Not Sell \"Pre-Blended\" Vials\u003c\/strong\u003e\u003cbr\u003eAt Tide Labs, we prioritize chemical integrity over convenience. While other vendors may sell single vials containing both peptides mixed together, we refuse to do so. BPC-157 and TB-500 have different molecular weights, pH stability requirements, and degradation rates. Mixing them in a solution for long-term storage or during the lyophilization process often leads to the degradation of one or both peptides before they even reach the lab bench.\u003cbr\u003eTo understand the science behind why separate vials are the only professional choice, read our full analysis: \u003ca href=\"https:\/\/tidelabs.co.uk\/blogs\/articles\/why-tide-labs-doesn-t-mix-bpc-157-tb-500-and-why-blended-vials-don-t-add-up\" title=\"Why Tide Labs Doesn't Mix BPC-157 \u0026amp; TB-500\" rel=\"noopener noreferrer\" target=\"_blank\"\u003eWhy Tide Labs Doesn't Mix BPC-157 \u0026amp; TB-500\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eArea of Interest\u003c\/h3\u003e\n\u003cp\u003eResearchers have investigated the BPC-157 + TB-500 combination across several areas of preclinical and laboratory study. The inclusion of bacteriostatic water allows for immediate and sterile reconstitution for experimental application:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue Healing:\u003c\/strong\u003e Both peptides are explored for their roles in supporting tendon, ligament, and muscle recovery in injury models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAngiogenesis \u0026amp; Blood Flow:\u003c\/strong\u003e TB-500 has been studied for promoting new blood vessel growth, while BPC-157 has been linked with protective effects on vascular tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory Potential:\u003c\/strong\u003e Evidence suggests both peptides may influence inflammatory pathways, making the concurrent study of these separate compounds highly relevant in chronic injury research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynergistic Effects:\u003c\/strong\u003e By combining BPC-157’s focus on gut and connective tissue repair with TB-500’s angiogenic and cellular migration properties, researchers are exploring whether the protocol offers a broader range of regenerative potential.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThis combination is regarded in research settings as a versatile and promising area of study within peptide science.\u003c\/p\u003e\n\u003ch3\u003eTechnical Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical Names:\u003c\/strong\u003e Pentadecapeptide BPC-157 \u0026amp; Thymosin Beta-4 Fragment (TB-500)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKit Contents:\u003c\/strong\u003e 1x BPC-157 (5mg), 1x TB-500 (5mg), 1x Bacteriostatic Water (10ml)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolvent Composition:\u003c\/strong\u003e Sterile Water with 0.9% Benzyl Alcohol (Bacteriostatic agent)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula (BPC-157):\u003c\/strong\u003e C₆₂H₉₈N₁₆O₂₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight (BPC-157):\u003c\/strong\u003e 1419.53 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula (TB-500):\u003c\/strong\u003e C₂₁₂H₃₅₀N₅₆O₇₈S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight (TB-500):\u003c\/strong\u003e ~4963 g\/mol (full Thymosin Beta-4 fragment equivalent)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeptide Classification:\u003c\/strong\u003e Synthetic peptides – BPC-157 derived from gastric protein, TB-500 derived from Thymosin Beta-4\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eStorage Guidelines\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLyophilized peptides (powder) are stable at room temperature for short periods.\u003c\/li\u003e\n\u003cli\u003eFor long-term storage of the powder vials, keep at −20°C or below.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacteriostatic Water:\u003c\/strong\u003e Store at room temperature (15–25°C). Do not freeze.\u003c\/li\u003e\n\u003cli\u003e\n\u003cp class=\"p1\"\u003eOnce reconstituted (mixed), store peptide solutions at 2–8 °C. The Benzyl Alcohol in the solvent preserves sterility for up to 28 days after opening.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSolubility\u003c\/h3\u003e\n\u003cp\u003eBoth peptides are fully soluble in the included Bacteriostatic Water. The 10ml volume allows for flexible concentration ratios depending on the specific requirements of the research protocol.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSikiric, P., Seiwerth, S., Grabarevic, Z., et al. (2001). “A new gastric juice peptide, BPC, heals both acute and chronic gastrointestinal lesions.” \u003cem\u003eJournal of Physiology (Paris)\u003c\/em\u003e, 95(1-6), 79–92. \u003ca rel=\"noopener noreferrer\" href=\"https:\/\/doi.org\/10.1016\/S0928-4257(01)00011-5\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1016\/S0928-4257(01)00011-5\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePhilp, D., Badamchian, M., Scheremeta, B., et al. (2003). “Thymosin beta4 and angiogenesis: initiation of new blood vessel growth.” \u003cem\u003eAnnals of the New York Academy of Sciences\u003c\/em\u003e, 1002, 168–177. \u003ca rel=\"noopener noreferrer\" href=\"https:\/\/doi.org\/10.1196\/annals.1283.018\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1196\/annals.1283.018\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eMalinda, K. M., Sidhu, G. S., Mani, H., et al. (1999). “Thymosin beta4 accelerates wound healing.” \u003cem\u003eJournal of Investigative Dermatology\u003c\/em\u003e, 113(3), 364–368. \u003ca rel=\"noopener noreferrer\" href=\"https:\/\/doi.org\/10.1046\/j.1523-1747.1999.00705.x\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1046\/j.1523-1747.1999.00705.x\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSeiwerth, S., Rucman, R., Turkovic, B., et al. (2014). “Stable gastric pentadecapeptide BPC 157: novel mediator of Robert’s cytoprotection and adaptive cytoprotection.” \u003cem\u003eCurrent Pharmaceutical Design\u003c\/em\u003e, 20(7), 1126–1135. \u003ca rel=\"noopener noreferrer\" href=\"https:\/\/doi.org\/10.2174\/13816128113199990435\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.2174\/13816128113199990435\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCertificate of Analysis (COA):\u003c\/strong\u003e See Images \u003c\/p\u003e","brand":"Tide Labs","offers":[{"title":"Default Title","offer_id":52357567840599,"sku":null,"price":42.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/BPTBBAC.webp?v=1782220533"},{"product_id":"systemic-repair-kit-ghk-bpc-tb-kpv","title":"Systemic Repair \u0026 Dermatological Research Kit (Quad-Compound) KLOW Blend","description":"\u003cp\u003e\u003cstrong\u003eThe Comprehensive Research Bundle: GHK-Cu, BPC-157, TB-500, KPV \u0026amp; Bacteriostatic Water.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis advanced research bundle combines the four most rigorously studied compounds in regenerative science into a single, synergistic toolset. The kit contains \u003cstrong\u003eGHK-Cu (50mg)\u003c\/strong\u003e, \u003cstrong\u003eBPC-157 (5mg)\u003c\/strong\u003e, \u003cstrong\u003eTB-500 (5mg)\u003c\/strong\u003e, \u003cstrong\u003eKPV (5mg)\u003c\/strong\u003e, and \u003cstrong\u003e10ml of Bacteriostatic Water\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eDesigned for broad-spectrum investigation, this set allows for simultaneous study of collagen synthesis, inflammatory signaling, and structural motility without the risks associated with pre-blended formulations.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCRITICAL: Why This Must Not Be Pre-Blended\u003c\/strong\u003e\u003cbr\u003eThis kit contains GHK-Cu (Copper Tripeptide-1). Copper ions are highly reactive in solution and can cause rapid hydrolysis (breakdown) of other peptide chains if mixed during manufacturing or long-term storage.\u003cbr\u003e\u003cstrong\u003eA \"pre-mixed\" vial of these four compounds is chemically flawed.\u003c\/strong\u003e By the time it reaches the researcher, the Copper may have degraded the BPC-157 and TB-500 structures.\u003cbr\u003eTo understand the science behind why separate vials are the only professional choice, read our full analysis: \u003ca href=\"https:\/\/tidelabs.co.uk\/blogs\/articles\/why-tide-labs-doesn-t-mix-bpc-157-tb-500-and-why-blended-vials-don-t-add-up\" title=\"Why Tide Labs Doesn't Mix Peptides\" rel=\"noopener\" target=\"_blank\"\u003eWhy Tide Labs Doesn't Mix Peptides \u0026amp; Why Blends Don't Add Up\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eArea of Interest\u003c\/h3\u003e\n\u003cp\u003eThis \"Quad-Compound\" set is frequently utilized in complex regenerative models involving multiple biological systems:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDermatological \u0026amp; Collagen Matrix:\u003c\/strong\u003e \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/ghk-cu\" title=\"GHK-Cu Research Peptide\"\u003eGHK-Cu\u003c\/a\u003e is widely researched for its ability to upregulate collagen and elastin production, potentially influencing skin remodeling and scar tissue reduction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSystemic Inflammation (Gut \u0026amp; Skin):\u003c\/strong\u003e \u003cstrong\u003eKPV\u003c\/strong\u003e (Keyhole Limpet Hemocyanin derived) and \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/bpc-157-research-peptide\" title=\"BPC-157 Research Peptide\"\u003eBPC-157\u003c\/a\u003e are investigated for their synergistic modulation of inflammatory cytokines, particularly in mucosal linings and dermal barriers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStructural \u0026amp; Musculoskeletal:\u003c\/strong\u003e \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/tb-500\" title=\"TB-500 Research Peptide\"\u003eTB-500\u003c\/a\u003e and BPC-157 provide the foundational research variables for cellular migration, angiogenesis, and tendon\/ligament recovery analysis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynergy:\u003c\/strong\u003e Researchers utilize this specific combination to study the overlap between \"surface\" repair (Skin\/Collagen) and \"deep\" repair (Muscle\/Connective Tissue).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTechnical Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKit Contents:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e1x GHK-Cu (50mg) - \u003cem\u003eBlue Lyophilized Cake\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli\u003e1x BPC-157 (5mg)\u003c\/li\u003e\n\u003cli\u003e1x TB-500 (5mg)\u003c\/li\u003e\n\u003cli\u003e1x KPV (5mg)\u003c\/li\u003e\n\u003cli\u003e1x Bacteriostatic Water (10ml)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacteriostatic Water Composition:\u003c\/strong\u003e Sterile Water with 0.9% Benzyl Alcohol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence (GHK-Cu):\u003c\/strong\u003e (Gly-His-Lys)2-Cu\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence (KPV):\u003c\/strong\u003e Lys-Pro-Val\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% (HPLC Verified Manufacturer Standard)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eStorage \u0026amp; Solubility\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu Stability:\u003c\/strong\u003e Hygroscopic. Keep sealed tightly. Store all powder vials at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution Note:\u003c\/strong\u003e GHK-Cu yields a blue solution. Other peptides yield a clear solution.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePickart, L., \u0026amp; Margolina, A. (2018). \"Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.\" \u003cem\u003eInternational Journal of Molecular Sciences\u003c\/em\u003e, 19(7), 1987. \u003ca rel=\"noopener noreferrer\" href=\"https:\/\/doi.org\/10.3390\/ijms19071987\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ijms19071987\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDalmasso, G., Charrier-Hisamuddin, L., Nguyen, H. T., et al. (2008). \"PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.\" \u003cem\u003eGastroenterology\u003c\/em\u003e, 134(1), 166–178. \u003ca rel=\"noopener noreferrer\" href=\"https:\/\/doi.org\/10.1053\/j.gastro.2007.10.026\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1053\/j.gastro.2007.10.026\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eSikiric, P., et al. (2010). \"Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease.\" \u003cem\u003eCurrent Pharmaceutical Design\u003c\/em\u003e, 16(10), 1224–1234.\u003c\/li\u003e\n\u003cli\u003eMalinda, K. M., et al. (1999). \"Thymosin beta4 accelerates wound healing.\" \u003cem\u003eJournal of Investigative Dermatology\u003c\/em\u003e, 113(3), 364–368.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Tide Labs","offers":[{"title":"Default Title","offer_id":52366859141463,"sku":null,"price":84.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/Klow.webp?v=1782220544"},{"product_id":"cognitive-signalling-set-semax-selank","title":"Cognitive Signalling Research Set (Semax \/ Selank)","description":"\u003cp\u003e\u003cstrong\u003eThe Neuropeptide Research Set: Semax \u0026amp; Selank (5mg).\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis synergistic toolset pairs two of the most distinct regulatory peptides in neuro-biological research. The set contains \u003cstrong\u003e1x \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/semax\"\u003eSemax (5mg)\u003c\/a\u003e\u003c\/strong\u003e and \u003cstrong\u003e1x \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/selank\"\u003eSelank (5mg)\u003c\/a\u003e\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eDesigned for the investigation of central nervous system signaling, this pairing allows for the simultaneous study of BDNF (Brain-Derived Neurotrophic Factor) expression and enkephalinase inhibition pathways using distinct peptide analogues.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCRITICAL: Chemical Stability Notice\u003c\/strong\u003e\u003cbr\u003eBoth Semax and Selank are heptapeptides known for their fragility in liquid state. Pre-mixed liquid solutions often suffer from rapid enzymatic degradation or hydrolysis.\u003cbr\u003eTide Labs supplies these as separate, lyophilized reagents to ensure the amino acid sequences remain intact until the exact moment of reconstitution for laboratory use.\u003c\/p\u003e\n\u003ch3\u003eAreas of Investigation\u003c\/h3\u003e\n\u003cp\u003eThis dual-compound set is utilized to compare and contrast two distinct signaling mechanisms in the CNS:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSemax (ACTH Analogue):\u003c\/strong\u003e Derived from the Adrenocorticotropic hormone fragment (ACTH 4-10), Semax is researched for its influence on BDNF expression and its potential role in neuroprotection and cognitive modeling during ischemic stress.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSelank (Tuftsin Analogue):\u003c\/strong\u003e A synthetic derivative of the immunomodulatory peptide Tuftsin. Research focuses on its interaction with GABA receptors and its potential to modulate anxiety-like behaviors in animal models via enkephalin stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynergistic Modulation:\u003c\/strong\u003e Researchers often utilize this pair to study the balance between \"Stimulatory\" neurogenesis (Semax) and \"Regulatory\" stress response (Selank).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTechnical Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eKit Contents:\u003c\/strong\u003e\n\u003cul\u003e\n\u003cli\u003e1x \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/semax\" title=\"Semax 5mg Peptide\"\u003eSemax (5mg)\u003c\/a\u003e - Lyophilized\u003c\/li\u003e\n\u003cli\u003e1x \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/selank\" title=\"Selank 5mg Peptide\"\u003eSelank (5mg)\u003c\/a\u003e - Lyophilized\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence (Semax):\u003c\/strong\u003e Met-Glu-His-Phe-Pro-Gly-Pro\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence (Selank):\u003c\/strong\u003e Thr-Lys-Pro-Arg-Pro-Gly-Pro\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e \u0026gt;99% (Manufacturer Standard)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolubility:\u003c\/strong\u003e Water Soluble\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eStorage \u0026amp; Handling\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLyophilized Stability:\u003c\/strong\u003e Store at -20°C. Stable for 24 months in powder form.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution:\u003c\/strong\u003e Gentle rotation is sufficient to dissolve. Do not shake vigorously (vortex) as this may damage the peptide bonds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eEremin, K. O., et al. (2005). \"Semax, an ACTH(4-10) analogue with neuroprotective properties.\" \u003cem\u003eJournal of Neurochemistry\u003c\/em\u003e. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15663124\/\" rel=\"noopener\" target=\"_blank\"\u003ePubMed Link\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eUchakin, P. N., et al. (2002). \"Phenotypic differences in the effects of Selank on active avoidance conditioning.\" \u003cem\u003eNeuroscience and Behavioral Physiology\u003c\/em\u003e. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12587680\/\" rel=\"noopener\" target=\"_blank\"\u003ePubMed Link\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCertificate of Analysis (COA):\u003c\/strong\u003e \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/SEMAX.pdf?v=1764673934\" rel=\"noopener\" target=\"_blank\"\u003eSemax Verified \u0026gt;99%\u003c\/a\u003e | \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/SELANK.pdf?v=1764673772\" rel=\"noopener\" target=\"_blank\"\u003eSelank Verified \u0026gt;99%\u003c\/a\u003e\u003c\/p\u003e","brand":"Tide Labs","offers":[{"title":"Default Title","offer_id":52376665948503,"sku":null,"price":33.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/semaxselankbundle.webp?v=1782220560"},{"product_id":"metabolic-efficiency-research-kit-nad-5-amino-1mq-blend","title":"Metabolic Efficiency Research Kit - NAD+ 1000mg \u0026 5-Amino-1MQ 10mg Blend","description":"\u003cp\u003e\u003cstrong\u003eCertificate of Analysis (COA): \u003ca rel=\"noopener\" title=\"Knowledge Hub\" href=\"https:\/\/tidelabs.co.uk\/pages\/knowledge-hub\" target=\"_blank\"\u003eAvailable Here\u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003eMetabolic Signaling Research Set\u003c\/strong\u003e is a dual-reagent kit featuring high-concentration \u003cstrong\u003e\u003ca href=\"https:\/\/tidelabs.co.uk\/products\/nad-research-peptide\"\u003eNAD⁺ (1000mg)\u003c\/a\u003e\u003c\/strong\u003e and \u003cstrong\u003e\u003ca href=\"https:\/\/tidelabs.co.uk\/products\/5-amino-1mq-10mg\"\u003e5-Amino-1MQ (10mg)\u003c\/a\u003e\u003c\/strong\u003e. This pairing is engineered for laboratories investigating the NAD+ salvage pathway and mitochondrial bioenergetics.\u003c\/p\u003e\n\u003cp\u003eThe synergy of this kit allows for the study of intracellular coenzyme levels from two distinct vectors. While exogenous NAD⁺ provides the direct substrate for sirtuin activation and ATP production, 5-Amino-1MQ acts as a membrane-permeable inhibitor of the enzyme Nicotinamide N-methyltransferase (NNMT). Research suggests that by blocking NNMT, 5-Amino-1MQ prevents the degradation of nicotinamide, theoretically preserving the endogenous pool of NAD⁺.\u003c\/p\u003e\n\u003ch3\u003eAreas of Research Interest\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial Bioenergetics:\u003c\/strong\u003e Evaluation of ATP production efficiency and electron transport chain stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNAD+ Flux Dynamics:\u003c\/strong\u003e Investigating the interplay between direct coenzyme supplementation and enzymatic inhibition of the salvage pathway.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdipocyte Metabolism:\u003c\/strong\u003e 5-Amino-1MQ is widely studied in models of white adipose tissue to observe shifts in cellular energy expenditure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Rejuvenation:\u003c\/strong\u003e Exploring the role of sirtuin signaling and DNA repair mechanisms in aged tissue models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003ch4\u003eComponent 1: NAD⁺ (1000mg)\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e 1000mg Lyophilized Cake\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical Name:\u003c\/strong\u003e Nicotinamide Adenine Dinucleotide (oxidized form)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₂₁H₂₇N₇O₁₄P₂\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 663.43 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 53-84-9\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e \u003ca rel=\"noopener\" href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/5893\" target=\"_blank\"\u003e5893\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eComponent 2: 5-Amino-1MQ (10mg)\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormat:\u003c\/strong\u003e 10mg Lyophilized Powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical Name:\u003c\/strong\u003e 5-amino-1-methylquinolinium\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClassification:\u003c\/strong\u003e Selective NNMT Inhibitor \/ Small Molecule\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 159.21 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 42464-96-0\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003ch3\u003eStorage \u0026amp; Stability Protocols\u003c\/h3\u003e\n\u003cp\u003eTo maintain sequence integrity and prevent denaturation, both compounds are supplied in \u003cstrong\u003eType 1 Hydrolytic Glass\u003c\/strong\u003e. Tide Labs utilizes a strict cold-chain infrastructure for all metabolic reagents.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLong-Term Storage (Lyophilized):\u003c\/strong\u003e Store at −20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution:\u003c\/strong\u003e Reagents are soluble in \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/bacteriostatic-water-10ml\"\u003e\u003cstrong\u003eBacteriostatic Water (10ml)\u003c\/strong\u003e\u003c\/a\u003e or sterile saline.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePost-Reconstitution:\u003c\/strong\u003e Store at 2–8°C. Rapid use is recommended to ensure data accuracy.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eTechnical References\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eNeelakantan, H., et al. (2019). “Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice.” \u003cem\u003eNature Medicine\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.1038\/s41591-019-0604-9\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1038\/s41591-019-0604-9\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eVerdin, E. (2015). “NAD⁺ in aging, metabolism, and neurodegeneration.” \u003cem\u003eScience\u003c\/em\u003e. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1126\/science.aac4854\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1126\/science.aac4854\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eCampagna, R., et al. (2021). “Nicotinamide N-methyltransferase (NNMT) in health and disease.” \u003cem\u003eCellular and Molecular Life Sciences\u003c\/em\u003e. \u003ca href=\"https:\/\/doi.org\/10.1007\/s00018-021-03909-6\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/s00018-021-03909-6\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFor further technical definitions, visit our \u003ca href=\"https:\/\/tidelabs.co.uk\/pages\/technical-index\"\u003e\u003cstrong\u003eTechnical Index\u003c\/strong\u003e\u003c\/a\u003e. Batch-specific testing data is available via our \u003ca href=\"https:\/\/tidelabs.co.uk\/pages\/knowledge-hub\"\u003e\u003cstrong\u003eKnowledge Hub\u003c\/strong\u003e\u003c\/a\u003e.\u003c\/p\u003e","brand":"Tide Labs ","offers":[{"title":"Default Title","offer_id":52819888603479,"sku":"TL-KIT-NAD-5AM-BLEND","price":102.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/nadand5amino.webp?v=1782220633"}],"url":"https:\/\/tidelabs.co.uk\/collections\/synergistic-research-kits.oembed","provider":"Tide Labs ","version":"1.0","type":"link"}