{"product_id":"ahk-cu-100mg","title":"AHK-Cu 100mg","description":"\u003cp\u003e\u003cstrong\u003eCertificate of Analysis (COA): Pending \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAHK-Cu (Copper Tripeptide-3)\u003c\/strong\u003e is a synthetic research peptide composed of three amino acids (alanine, histidine, lysine) complexed with a copper ion. Structurally a close cousin of GHK-Cu, AHK-Cu has become a focused subject of preclinical investigation, particularly in studies relating to hair follicle biology, dermal cell research, and copper-mediated signalling pathways. While not approved for human or veterinary use, AHK-Cu continues to generate strong interest as a research compound across cellular and tissue model studies.\u003c\/p\u003e\n\u003ch3\u003eArea of Interest\u003c\/h3\u003e\n\u003cp\u003eResearch on AHK-Cu has focused on several areas of interest:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Follicle Biology:\u003c\/strong\u003e Investigated in models examining follicle elongation, anagen phase activity, and dermal papilla cell behaviour in vitro.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDermal Cell Research:\u003c\/strong\u003e Studied in fibroblast and keratinocyte models, where research has explored proliferation, viability, and extracellular matrix dynamics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVascular Signalling:\u003c\/strong\u003e Preclinical studies have examined AHK-Cu in relation to vascular endothelial growth factor (VEGF) expression and angiogenic pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper-Mediated Pathways:\u003c\/strong\u003e Research has explored its role as a copper-binding tripeptide in cellular signalling, antioxidant defence, and collagen-related biological models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTogether, these studies position AHK-Cu as an actively investigated peptide in dermal and follicular research, complementing the broader body of work on copper-binding peptides.\u003c\/p\u003e\n\u003ch3\u003eTechnical Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical Name:\u003c\/strong\u003e Copper Tripeptide-3 (Alanyl-Histidyl-Lysine Copper Complex)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e AHK-Cu, Ala-His-Lys-Cu, Copper Tripeptide 3\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₁₅H₂₅CuN₆O₄ (peptide-copper complex)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e approximately 416.94 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence (Amino Acid):\u003c\/strong\u003e Ala-His-Lys (AHK)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 767286-83-9\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeptide Classification:\u003c\/strong\u003e Synthetic copper-binding tripeptide\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eStorage Guidelines\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLyophilized peptide is stable at room temperature for several weeks.\u003c\/li\u003e\n\u003cli\u003eFor long-term storage, keep at −20°C or below.\u003c\/li\u003e\n\u003cli\u003eOnce reconstituted, store at 2–8 °C. Effective use depends on the solution used.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSolubility\u003c\/h3\u003e\n\u003cp\u003eAHK-Cu is soluble in sterile water and bacteriostatic water. Avoid acidic buffers or low-pH solutions which may destabilise the copper complex.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePyo, H.K., Yoo, H.G., Won, C.H., et al. (2007). \"The effect of tripeptide-copper complex on human hair growth in vitro.\" \u003cem\u003eArchives of Pharmacal Research\u003c\/em\u003e, 30(7), 834–839. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1007\/BF02978835\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/BF02978835\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePickart, L., Vasquez-Soltero, J.M., Margolina, A. (2015). \"GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration.\" \u003cem\u003eBioMed Research International\u003c\/em\u003e, 2015, 648108. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1155\/2015\/648108\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1155\/2015\/648108\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003ePickart, L., Margolina, A. (2018). \"Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data.\" \u003cem\u003eInternational Journal of Molecular Sciences\u003c\/em\u003e, 19(7), 1987. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.3390\/ijms19071987\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.3390\/ijms19071987\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Tide Labs","offers":[{"title":"Default Title","offer_id":53515651449175,"sku":null,"price":44.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/AHK-CuMain.png?v=1779833332","url":"https:\/\/tidelabs.co.uk\/products\/ahk-cu-100mg","provider":"Tide Labs ","version":"1.0","type":"link"}