{"product_id":"vesugen-research-peptide","title":"Vesugen","description":"\u003cp\u003e\u003cstrong\u003eCertificate of Analysis (COA): See Images\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVesugen (Lys-Glu-Asp)\u003c\/strong\u003e is a synthetic research tripeptide and a vascular-associated member of the Khavinson family of short peptide bioregulators. Derived from a sequence related to vascular wall proteins, Vesugen has become an exciting subject of study in preclinical research, particularly in areas related to vascular endothelial cells, gene expression, and neuronal signalling. While not approved for human or veterinary use, Vesugen continues to generate strong interest as a promising candidate in laboratory and academic research settings.\u003c\/p\u003e\n\u003ch3\u003eArea of Interest\u003c\/h3\u003e\n\u003cp\u003eResearch on Vesugen has focused on several areas of interest:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eVascular Endothelial Studies:\u003c\/strong\u003e Investigated in preclinical models for its influence on the proliferation and behaviour of vascular endothelial cells, the cells that line blood vessels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene Expression Regulation:\u003c\/strong\u003e Studied for its ability to influence tissue-specific transcriptional activity, including reported effects on endothelin-1 and connexin expression, a defining characteristic of the Khavinson bioregulator family.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuronal Spine Density:\u003c\/strong\u003e Examined in primary hippocampal neuron cultures, where research reported an increase in mushroom spine density under synaptotoxic conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGeroprotective Research:\u003c\/strong\u003e Explored as an ultra-short peptide of interest in studies of age-associated vascular change and cellular homeostasis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTogether, these studies position Vesugen as a distinctive ultra-short bioregulator. It is frequently investigated alongside related Khavinson peptides such as \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/cortagen-research-peptide\"\u003eCortagen\u003c\/a\u003e and \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/pancragen-research-peptide\"\u003ePancragen\u003c\/a\u003e, reflecting its potential as an exciting area of discovery in peptide bioregulation.\u003c\/p\u003e\n\u003ch3\u003eTechnical Information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical Name:\u003c\/strong\u003e L-Lysyl-L-α-glutamyl-L-α-aspartic acid\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynonyms:\u003c\/strong\u003e KED, T-38, Lys-Glu-Asp\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₁₅H₂₆N₄O₈\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 390.39 g\/mol\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence (Amino Acid):\u003c\/strong\u003e Lys-Glu-Asp (KED)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 204271-66-9\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePeptide Classification:\u003c\/strong\u003e Synthetic Khavinson short peptide bioregulator (tripeptide)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eStorage Guidelines\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eLyophilized peptide is stable at room temperature for several weeks.\u003c\/li\u003e\n\u003cli\u003eFor long-term storage, keep at −20°C or below.\u003c\/li\u003e\n\u003cli\u003e\n\u003cmeta charset=\"UTF-8\"\u003e\n\u003cp class=\"p1\"\u003eOnce reconstituted, store at 2–8 °C. Effective use depends on the solution used.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSolubility\u003c\/h3\u003e\n\u003cp\u003eVesugen is soluble in \u003ca href=\"https:\/\/tidelabs.co.uk\/products\/bacteriostatic-water-10ml\"\u003ebacteriostatic water\u003c\/a\u003e and other aqueous buffers depending on purity and formulation.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eKhavinson, V. K., Kuznik, B. I., \u0026amp; Ryzhak, G. A. (2013). \"Peptide bioregulators: a new class of geroprotectors.\" \u003cem\u003eAdvances in Gerontology\u003c\/em\u003e, 3(3), 225–235. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1134\/S2079057013030089\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1134\/S2079057013030089\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKraskovskaya, N. A., Kukanova, E. O., Lin'kova, N. S., et al. (2017). \"Tripeptides Restore the Number of Neuronal Spines under Conditions of In Vitro Modeled Synaptotoxicity.\" \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 163(4), 550–553. \u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28853087\/\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/28853087\/\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eKhavinson, V. K., Lin'kova, N. S., Polyakova, V. O., et al. (2012). \"Peptides tissue-specifically stimulate cell differentiation during their aging.\" \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e, 153(1), 148–151. \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1007\/s10517-012-1664-1\" target=\"_blank\"\u003ehttps:\/\/doi.org\/10.1007\/s10517-012-1664-1\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Tide Labs","offers":[{"title":"10mg","offer_id":53708846530903,"sku":"TL-VESU-10MG","price":44.95,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/3142\/1527\/files\/vesugen_10mg_vial.webp?v=1780589491","url":"https:\/\/tidelabs.co.uk\/products\/vesugen-research-peptide","provider":"Tide Labs ","version":"1.0","type":"link"}