Why We Don’t Mix BPC-157 & TB-500 — and Why Many Labs Avoid Blended Vials

Blended peptide vials might look convenient, but in research settings they create measurement uncertainty, remove control, and make it impossible to interpret results. Here’s why separate vials remain the preferred approach across most lab workflows.

Key takeaways

Unknown ratios: once two peptides are combined, you have no verifiable way to know the exact amount of each compound per mL.
Harder to benchmark: when results change, you cannot isolate which peptide contributed to the outcome.
Storage differences: peptides often have different stability profiles — mixing forces a compromise.
Supplier convenience ≠ research accuracy: blended vials are cheaper to produce but introduce uncertainty for the end user.

What researchers measure

In controlled environments, researchers track variables individually: concentration, solvent choice, reconstitution amount, aliquots, and degradation rate. When two peptides are mixed into one vial, none of those values remain independently measurable.

Why blends introduce uncertainty

No ratio transparency: even if a supplier claims “2.5 mg + 2.5 mg”, you can’t confirm distribution is uniform after lyophilisation.
Interference risk: peptides can degrade differently depending on pH, solvent, and temperature. One may destabilise the other.
Impossible to replicate: you cannot recreate conditions or compare against other studies because the internal composition is unknown.
Loss of control: adjusting one variable becomes impossible when both peptides depend on each other’s concentration.

Blends are cheaper to manufacture — not better for research accuracy. Separate vials mean control, clarity, and replicability.

Why some suppliers offer blends

Lower production cost: one vial, one stopper, one label = cheaper for the supplier.
Marketing appeal: “two-in-one” sounds convenient even though it reduces control.
Less scrutiny: blends make it harder for customers to compare mg-per-vial pricing between suppliers.

Why Tide Labs keeps compounds separate

Every compound remains in its own vial so researchers can track lot numbers, storage behaviour, reconstitution choices, and concentration independently. This supports traceability and reduces ambiguity — essential for clean laboratory work.

Quick reference table

Factor	Separate vials	Blended vial
Known concentration	✔ Independent	✖ Not measurable
Replicability	✔ High	✖ Low
Stability	✔ Controlled per peptide	✖ Forced compromise
Cost to supplier	Higher	Lower