The Neuropeptide Research Set: Semax & Selank (5mg).

This synergistic toolset pairs two of the most distinct regulatory peptides in neuro-biological research. The set contains 1x Semax (5mg) and 1x Selank (5mg).

Designed for the investigation of central nervous system signaling, this pairing allows for the simultaneous study of BDNF (Brain-Derived Neurotrophic Factor) expression and enkephalinase inhibition pathways using distinct peptide analogues.

CRITICAL: Chemical Stability Notice
Both Semax and Selank are heptapeptides known for their fragility in liquid state. Pre-mixed liquid solutions often suffer from rapid enzymatic degradation or hydrolysis.
Tide Labs supplies these as separate, lyophilized reagents to ensure the amino acid sequences remain intact until the exact moment of reconstitution for laboratory use.

Areas of Investigation

This dual-compound set is utilized to compare and contrast two distinct signaling mechanisms in the CNS:

• Semax (ACTH Analogue): Derived from the Adrenocorticotropic hormone fragment (ACTH 4-10), Semax is researched for its influence on BDNF expression and its potential role in neuroprotection and cognitive modeling during ischemic stress.
• Selank (Tuftsin Analogue): A synthetic derivative of the immunomodulatory peptide Tuftsin. Research focuses on its interaction with GABA receptors and its potential to modulate anxiety-like behaviors in animal models via enkephalin stability.
• Synergistic Modulation: Researchers often utilize this pair to study the balance between "Stimulatory" neurogenesis (Semax) and "Regulatory" stress response (Selank).

Technical Information

• Kit Contents:
  • 1x Semax (5mg) - Lyophilized
  • 1x Selank (5mg) - Lyophilized
• Sequence (Semax): Met-Glu-His-Phe-Pro-Gly-Pro
• Sequence (Selank): Thr-Lys-Pro-Arg-Pro-Gly-Pro
• Purity: >99% (Manufacturer Standard)
• Solubility: Water Soluble

Storage & Handling

• Lyophilized Stability: Store at -20°C. Stable for 24 months in powder form.
• Reconstitution: Gentle rotation is sufficient to dissolve. Do not shake vigorously (vortex) as this may damage the peptide bonds.

References

• Eremin, K. O., et al. (2005). "Semax, an ACTH(4-10) analogue with neuroprotective properties." Journal of Neurochemistry. PubMed Link
• Uchakin, P. N., et al. (2002). "Phenotypic differences in the effects of Selank on active avoidance conditioning." Neuroscience and Behavioral Physiology. PubMed Link

Certificate of Analysis (COA): Semax Verified >99% | Selank Verified >99%