GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic research peptide belonging to the growth hormone secretagogue family. It has been studied for its ability to stimulate growth hormone release through interaction with ghrelin receptors, making it a peptide of significant interest in both metabolic and regenerative research. While not approved for human or veterinary use, GHRP-2 continues to generate attention as an exciting subject of laboratory and academic exploration.

Area of Interest

Research into GHRP-2 has focused on several promising areas:

• Growth Hormone Release: Studied for its ability to stimulate endogenous GH secretion through pituitary and hypothalamic pathways.
• Metabolic Studies: Explored in relation to appetite regulation, fat metabolism, and lean mass development in preclinical models.
• Regenerative Research: Investigated for its potential impact on recovery, repair, and tissue growth in various experimental systems.
• Synergistic Models: Often studied in combination with other secretagogues such as GHRP-6, CJC-1295, or Ipamorelin for additive effects.

Together, these findings place GHRP-2 among the more widely researched growth hormone secretagogues, making it a peptide of ongoing interest for laboratory studies.

Technical Information

• Chemical Name: Growth Hormone Releasing Peptide-2
• Synonyms: GHRP-2, KP-102
• Molecular Formula: C₄₅H₅₅N₉O₆
• Molecular Weight: ~818.0 g/mol
• Sequence (Amino Acid): D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
• CAS Number: 158861-67-7
• Peptide Classification: Synthetic hexapeptide, growth hormone secretagogue

Storage Guidelines

• Lyophilized peptide is stable at room temperature for short periods.
• For long-term storage, keep at −20 °C or below.
• Once reconstituted, store at 2–8 °C. Effective use period may vary depending on the solution used.

Solubility

GHRP-2 is soluble in sterile water, acetic acid, or other aqueous buffers depending on formulation and purity.

References

• Bowers, C. Y. (1998). “Growth hormone-releasing peptide (GHRP).” Cellular and Molecular Life Sciences, 54(12), 1316–1329. https://doi.org/10.1007/s000180050246
• Smith, R. G., Van der Ploeg, L. H., Howard, A. D., et al. (1997). “Peptidomimetic regulation of growth hormone secretion.” Endocrine Reviews, 18(5), 621–645. https://doi.org/10.1210/edrv.18.5.0316
• Bowers, C. Y., Momany, F., Reynolds, G. A., et al. (1984). “Structure–activity relationships of a synthetic pentapeptide that specifically releases growth hormone in vitro.” Endocrinology, 114(5), 1537–1545. https://doi.org/10.1210/endo-114-5-1537

Certificate of Analysis (COA): Available here