Thymalin is a synthetic peptide derived from extracts of the thymus gland, an organ central to immune system development and regulation. First studied in the Soviet Union, Thymalin has been investigated for decades as part of research into immune modulation, aging, and cellular homeostasis. It remains a subject of scientific interest for its potential role in regulating immune responses and supporting cellular balance in laboratory settings.

Area of Interest

Research into Thymalin has focused on several key areas:

• Immune Regulation: Studied for its role in stimulating T-cell production and balancing immune responses in models of immune suppression.
• Aging Research: Explored for its potential to influence biomarkers of aging, including immune decline and oxidative stress.
• Cellular Homeostasis: Investigated in preclinical studies for its effects on protein synthesis, DNA repair, and apoptosis regulation.
• Chronic Conditions: Some research has evaluated its potential use in models of chronic disease linked to immune dysfunction.

Together, these research areas highlight Thymalin as a peptide of long-standing interest, particularly in the fields of immunology and gerontology research.

Technical Information

• Chemical Name: Thymic peptide (Thymalin)
• Synonyms: Thymic extract peptide, Immunomodulatory peptide
• Molecular Formula: Varies depending on preparation – typically small thymic peptides
• Molecular Weight: ~800–1200 g/mol (range depending on fragment)
• Peptide Classification: Synthetic thymic peptide, immunomodulatory research peptide

Storage Guidelines

• Lyophilized peptide is stable at room temperature for short periods.
• For long-term storage, keep at −20 °C or below.
• Once reconstituted, store at 2–8 °C. Effective use depends on the solution used.

Solubility

Thymalin is soluble in sterile water and other aqueous buffers depending on purity and formulation.

References

• Khavinson, V. K., & Morozov, V. G. (2003). "Peptide thymic preparation Thymalin normalizes immunity in aging and immunodeficiency." Bulletin of Experimental Biology and Medicine, 136(3), 248–250. https://doi.org/10.1023/A:1024812017166
• Khavinson, V. K., Linkova, N. S., Dyatlova, A. S., et al. (2016). "Effect of thymic peptides on biomarkers of aging." Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology, 10(4), 299–307. https://doi.org/10.1134/S1990747816040092
• Morozov, V. G., & Khavinson, V. K. (1997). "Peptide bioregulators in the therapy of age-related pathology." Annals of the New York Academy of Sciences, 719, 293–306. https://doi.org/10.1111/j.1749-6632.1997.tb48573.x

Certificate of Analysis (COA): Available here